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Blue Jays enter matchup with the Astros on losing streak

Toronto Blue Jays (12-12, third in the AL East) vs. Houston Astros (12-11, second in the AL West) Houston; Wednesday, 7:40 p.m. EDT PITCHING PROBABLES: Blue Jays: Bowden Francis (2-2, 3.13 ERA, 1.04 WHIP, 20 strikeouts); Astros: Ryan Gusto (2-1, 3.

Orioles bring road losing streak into matchup against the Nationals

Baltimore Orioles (9-13, fourth in the AL East) vs. Washington Nationals (10-13, fourth in the NL East) Washington; Wednesday, 6:45 p.m. EDT PITCHING PROBABLES: Orioles: Tomoyuki Sugano (2-1, 3.43 ERA, 1.

Marlins aim to sweep 3-game series against the Reds

Cincinnati Reds (11-13, third in the NL Central) vs. Miami Marlins (11-12, third in the NL East) Miami; Wednesday, 1:10 p.m. EDT PITCHING PROBABLES: Reds: Brady Singer (3-0, 3.80 ERA, 1.

Rays aim to stop 4-game road slide, play the Diamondbacks

Tampa Bay Rays (9-14, fifth in the AL East) vs. Arizona Diamondbacks (14-9, fourth in the NL West) Phoenix; Wednesday, 9:40 p.m. EDT PITCHING PROBABLES: Rays: Taj Bradley (2-1, 5.24 ERA, 1.

Phillies take on the Mets looking to stop road slide

Philadelphia Phillies (13-11, second in the NL East) vs. New York Mets (17-7, first in the NL East) New York; Wednesday, 1:10 p.m. EDT PITCHING PROBABLES: Phillies: Zack Wheeler (2-1, 3.73 ERA, 0.99 WHIP, 41 strikeouts); Mets: David Peterson (1-1, 3.

Turang leads Brewers against the Giants following 4-hit performance

Milwaukee Brewers (13-11, second in the NL Central) vs. San Francisco Giants (15-9, third in the NL West) San Francisco; Wednesday, 9:45 p.m. EDT PITCHING PROBABLES: Brewers: Freddy Peralta (2-1, 1.91 ERA, 1.

Red Sox face the Mariners leading series 1-0

Seattle Mariners (12-11, third in the AL West) vs. Boston Red Sox (14-11, second in the AL East) Boston; Wednesday, 6:45 p.m. EDT PITCHING PROBABLES: Mariners: Emerson Hancock (0-1, 12.71 ERA, 2.

Braves square off against the Cardinals in series rubber match

St. Louis Cardinals (10-14, fourth in the NL Central) vs. Atlanta Braves (9-14, fifth in the NL East) Atlanta; Wednesday, 12:15 p.m. EDT PITCHING PROBABLES: Cardinals: Miles Mikolas (0-2, 7.64 ERA, 1.

Rockies aim to stop 11-game road losing streak, play the Royals

Colorado Rockies (4-18, fifth in the NL West) vs. Kansas City Royals (10-14, third in the AL Central) Kansas City, Missouri; Wednesday, 7:40 p.m. EDT PITCHING PROBABLES: Rockies: German Marquez (0-3, 8.27 ERA, 1.

Tigers and Padres play with series tied 1-1

San Diego Padres (17-7, first in the NL West) vs. Detroit Tigers (14-10, second in the AL Central) Detroit; Wednesday, 1:10 p.m. EDT PITCHING PROBABLES: Padres: Kyle Hart (2-1, 6.48 ERA, 1.38 WHIP, 10 strikeouts); Tigers: Reese Olson (2-1, 4.